Shen et al revealed that this method can also reduce serum levels of LH, LH/FSH, hirsuteness, and acne incidence while improving ovulation rate.[85] Acupuncture treatment can support the body, improve kidney function, strengthen the spleen, and regulate qi and blood flow by selecting appropriate acupoint pairings, such as Sanyinjiao (SP6), Guanyuan (RN4), Zigong (EX-CA1), Zhongji (RN3), and Qihai (RN6).[86] Additionally, acupuncture can be tailored to address specific symptoms by adding or subtracting acupressure points. This evidence concerns the gene PLOD1 and acne.