NFKB1 and neoplasm: Given that consecutive gene set enrichment analysis (GSEA) of highest-ranking gene sets based on transcriptomic profile of mRNA expression showed a signature for NF-κB pathway that was augmented upon depletion of RBM7 (Figure 6D), we suspected that the transcriptional activation of downstream genes in NF-κB signaling known to facilitate tumor angiogenesis might be involved in shRBM7-exerted pro-metastatic function.