To determine whether the efficacy of FS120m is dependent on IFNγ produced specifically by Tregs and their lineage-instable progeny, we treated Ifngfl/flFoxp3EGFP-Cre-ERT2 and IfngWTFoxp3EGFP-Cre-ERT2 mice with tamoxifen before tumor implantation. This evidence concerns the gene MAPK3 and neoplasm.