SLC6A3 and Alzheimer disease: Interestingly, another study by Matsuoka and colleagues aiming to identify differences in NPS between preclinical/prodromal AD and prodromal PDD/DLB demonstrated that MBI was related to both amyloid pathology assessed by PET and putative Lewy body pathology assessed by dopamine transporter single photon emission computed tomography (DAT-SPECT) [64].