Analyses of mouse irf2 promoter regions by ChIP demonstrated that after IFNβ and IFNBCOL01 treatment, enrichment of pSTAT1 increased in the promoter regions of the irf2 gene in −2000 to +2000 regions in RAW264.7 cells (Figure 6C), and in −2000 to 0, +1000 to +2000 regions in tumor-infiltrating CD11b+ cells (Figure 6D). This evidence concerns the gene ITGAM and neoplasm.