Next, we evaluated transcription of genes encoding PAOX and other polyamine-metabolizing proteins by RT-qPCR in several human cell lines, including Huh7.5 (hepatoma), A549 (lung adenocarcinoma), DU145 (prostate carcinoma), HeLa (cervix adenocarcinoma), and K562 (chronic myeloid leukemia). Here, PAOX is linked to chronic myelogenous leukemia, BCR-ABL1 positive.