SLC17A7 and schizophrenia: Interestingly, chronic administration of delta-9-THC during adolescence at a dose of 10 mg/kg increases VGLUT1 during adulthood in the medial prefrontal cortex (mPFC) and was associated with schizophrenia-like behaviors in rodents [56], which may help explain why cannabis use is a predisposing or risk factor for schizophrenia in humans [57,58].