Furthermore, since 53% of lung adenocarcinoma have a mutation in the TP53 gene [73], our model with a deleted p53 complements other models with a p53 mutation (CMT54 and CMT55) or models that express wild-type TP53 (CMT 167 and mKRC.1 [72]). This evidence concerns the gene TP53 and lung adenocarcinoma.