MLIP and heart failure: Furthermore, it is crucial to understand the potential off-target effects and safety profile of any MLIP-targeting therapies due to MLIP’s role in non-cancerous cells and processes, especially within the context of cardiac tissue where MLIP deficiency increase the susceptibility to developing heart failure [28,31] In summary, the modulation of MLIP’s function or its interactions with key signaling pathways represents a promising approach for the development of novel cancer therapeutics.