Consequently, the investigators isolated the T cell population in the GBM tumor samples and found a less proliferative HSP-expressing CD8+ HSP HSPA1A subgroup and minimal proliferative CD4+ HSP HSPA1A phenotypes that correlate with IL-10 levels, supporting the hypothesis that anti-tumoral immunity in GBMs is relatively weak. The gene discussed is HSPA1A; the disease is neoplasm.