The tumor regression grade (TRG 0–3) was defined according to the percentage of viable cancer cells in the resected primary tumor (Figure 7G).[33] The High p‐eIF4E group had significantly higher major response rate (TRG0/1) compared to the Low p‐eIF4E group (Figure 7H), indicating that EBV‐positive GC patients with hyper‐phosphorylation level of eIF4E would gain better response from immunotherapy. The gene discussed is EIF4E; the disease is neoplasm.