Furthermore, SCD1 also governs the Wnt signaling pathway in CSCs (El-Sahli et al., 2019) and has been observed to play a crucial role in the maintenance of stem cells in various other cancers, including melanoma, hepatocellular carcinoma (HCC), and colon cancer (Pisanu et al., 2018; Choi et al., 2019; Ma et al., 2019). The gene discussed is SCD; the disease is hepatocellular carcinoma.