TNNI3 and angina pectoris: And, NXT combination can better lower the frequency and duration of angina pectoris and reduce the serum cardiac troponinI (cTnI), CK-MB, myoglobin (MYO), myeloperoxidase (MPO) and lipid peroxide (LPO) levels, while elevate the left ventricular ejection fraction (LVEF) and stroke-volume (SV), suggesting that adding NXT to ticagrelor helped a lot in patients with CSA, especially in improving cardiac function and reducing angina pectoris symptoms (Qiu et al., 2023).