Depletion of CEBPB in these two GBM cell lines not only significantly decelerated the growth of GBM cells but also markedly decreased the expression level of monocyte chemoattractant protein-1 (CCL2) (Figure 5C, Figure S13B-C), a crucial factor in mediating the chemotactic migration of macrophages. The gene discussed is CCL2; the disease is glioblastoma.