Among the patients who underwent screening MRI for aknown mutation, the main mutations observed were as follows: BRCA1 (n = 17);BRCA2 (n = 16); P53 (n = 25); CHEK2 (n = 4); and othermutations (n = 5), including PALB2, CDH1, MLH1 (associated with Lynch syndrome),RET, and a variant of uncertain significance in the POLEgene. The gene discussed is CHEK2; the disease is Lynch syndrome.