However, there has been strong evidence arguing the correlation between CHST4, SLC22A8, STC2 (Carbohydrate sulfotransferase 4, Solute carrier family 22 member 8, Stanniocalcin-2), hsa-miRNA-326, and hsa-miRNA-21 with a strong potential for predicting prognosis in HCC patients specifically with sa-miRNA-326 andhsa-miRNA-21-5p have been found to have associations with multiple cancer-related pathways (Hu et al., 2021). This evidence concerns the gene CHST4 and hepatocellular carcinoma.