Likewise, in patients that received allogeneic HCT with total lymphoid irradiation (TLI) and anti-thymocyte globulin (ATG) conditioning, we revealed increased persistence of iNKT compared to CD4+ and CD8+ T cells post-TLI/ATG and protection against acute GVHD in patients with residual iNKT cells than those without detectable iNKT cells (211). The gene discussed is CD8A; the disease is graft versus host disease.