It's important to note that dysregulation of T cells is widely recognized to play a crucial role in the pathogenesis of several kidney diseases, with the Th17/IL17 axis commonly implicated in contributing to renal tissue damage in conditions such as SLE, IgA nephropathy, Type 2 diabetic nephropathy, hypertension (50–54). Here, IL17A is linked to IgA glomerulonephritis.