,53,54,55,56 SNS-032 is a CDK inhibitor targeting CDK2, 7 and 957,58 that exerts several anti-cancer effects, including reducing cell growth, inducing apoptosis, and inhibiting angiogenesis and invasion in various cancer types, including esophageal cancer, AML, breast cancer, and multiple myeloma.59 The gene discussed is CDK2; the disease is acute myeloid leukemia.