In terms of the 111 EC tumors with 279 tumor-specific mutations, 107 mutations occur in complex I genes, and the majority occur in ND5 (11 in ND1, 14 in ND2, 9 in ND3, 24 in ND4, 3 in ND4L, 36 in ND5, and 10 in ND6). Here, MT-ND5 is linked to neoplasm.