Among these RALY-bound transcripts, we noted several proliferation-related genes, six of which (HNRNPC, CHD4, HNRNPA2B1, PCBP2, STIP1 and USP22 24-29) showed elevated expression in HCC tissues and were linked to unfavorable patient outcomes (Figure S4). Here, USP22 is linked to hepatocellular carcinoma.