S-588410 is a cancer peptide vaccine comprised of five human leukocyte antigen (HLA)-A*24:02-restricted epitope peptides derived from five cancer-testis antigens: DEP domain-containing 1 (DEPDC1), M-phase phosphoprotein 1 (MPHOSPH1), up-regulated lung cancer 10 (URLC10), cell division cycle-associated protein 1 (CDCA1), and KH domain-containing protein overexpressed in cancer 1 (KOC1). The gene discussed is LY6K; the disease is cancer.