CPEB2 and Anxiety: The loss of CPEB2 in glutamatergic neurons sufficiently impaired glutamatergic transmission and long-term plasticity (Fig. 3F-H), so we examined the behavior of CPEB2-cKOVglut2 mice and found no abnormalities in their exploratory activity in the open field (Fig. 4A), anxiety level in the elevated plus maze (Fig. 4B), and spatial learning in the Morris water maze (Fig. 4C).