RUNX1 and precursor B-cell acute lymphoblastic leukemia: By analyzing the INPP5D expression from the leukemia dataset of Kohlmann et al. [41], GSE13204 we observed that the SHIP1 mRNA expression was differentially expressed across all B-ALL subtypes and increased in the group of ETV6-RUNX1-positive B-ALL and in the group of BCR-ABL-positive B-ALL, in comparison to other translocations within the B-ALL and compared to healthy hematopoietic cells (Fig. S1A).