Blocking neutrophil accumulation during emergency granulopoiesis also induced a progressive Hgb decline in Fancc−/−Tp53+/− mice (Fig. 1C); resulting in relative anemia compared to Fancc−/−Tp53+/− mice injected with Alum alone (p = 0.009, n = 6). Here, FANCC is linked to anemia (phenotype).