However, being multifactorial disorders [43], increasing attention is being paid to the overarching influence of pathological processes like inflammation [5, 9], including the effects the interplay between pathophysiological conditions, VEGFR1 ligands, pro-inflammatory factors, and the cells from which they originate, have upon the pathogenesis and progression of AMD and DR [7, 9, 44, 45]. Here, FLT1 is linked to age-related macular degeneration.