Interestingly, both infection types induced expression of the glycolysis marker ALDOC, but this induction was completely reversed by day3 p.i. in both types of infected NHNE, indicating that the increased expression of glycolysis that is also evident in the dual RNAseq data occurs likely as a result of the presence of LPS and is not modulated by live NTHi. Here, ALDOC is linked to infection.