APLN and cancer: These databases were searched for information about the importance of the apelinergic system in doxorubicin-induced cardiotoxicity using the following phrases: “anthracycline cardiotoxicity, apelin, apelin receptor, apelinergic system, apelin, cancer, cardioprotective therapy, chemotherapy, elabela, doxorubicin, doxorubicin cardiotoxicity, oncotreatment” in a variety of combinations.