HMOX1 and acute respiratory distress syndrome: Previous studies have provided evidence that the PI3K/AKT/mTOR and Keap1‐Nrf2/HO‐1 signalling pathways are involved in the development of ALI,34, 35 and traditional Chinese herbal medicine PL can exert its pharmacologic effect by regulating the PI3K/AKT/mTOR and Nrf2 signalling pathway.30, 36