To investigate the effects of microbiota from donors including Macaca fascicularis (Mcc), Bama miniature pigs (BP), beagle dogs (BD), and C57BL/6 J mice (Mice) on colitis, mice were colonized with fecal suspensions of Mcc, BP, BD, Mice, or saline and then treated with 3% DSS. This evidence concerns the gene MCC and colitis.