TSC1 and tuberous sclerosis: Folliculocystic and collagen hamartoma (FCCH) is a rare and relatively recently identified entity, predominantly affecting males with tuberous sclerosis complex. Tuberous sclerosis complex is an autosomal dominant genetic disorder arising from heterozygous mutations in the TSC1 or TSC2 tumor suppressor genes and is marked by the formation of hamartomas in various organs such as the brain, heart, skin, eyes, kidneys, lungs, and liver.