BRCA2 and neoplasm: We found only three PDXs classified as HRD expressing high levels of BRCA1 foci: two of them are BRCA2-mutated (i.e., MNHOC241 and MNHOC280, Supplementary Table S1), so they might correctly form BRCA1 foci, while the third model is a BRCA1/2 wild-type tumor (i.e., MNHOC135) but classified as HRD based on the HRDetect genomic test.