BIRC5 and hepatocellular carcinoma: In fact, this RP mediates specific oncogenic translation programs, modulating the translation of Myc and other mRNAs that encode for growth and survival factors (such as survivin and BCL-2) (50), and cell cycle regulators (such as Cyclin D1, D3 and B1) (55), in both neuroblastoma and hepatocellular carcinoma (HCC), respectively.