SHBG and metabolic syndrome: They revealed that men with lower concentrations of TT, SHBG, or FT were more likely to have prevalent MetS (ORs per quartile decrease were 1.69 (95% CI 1.60–1.77), 1.73 (95% CI 1.62- 1.85), and 1.46 (95% CI 1.36–1.57) for TT, SHBG, and FT, respectively) and incident MetS (HRs per quartile decrease were 1.25 (95% CI 1.16–1.36), 1.44 (95% 1.30–1.60) and 1.14 (95% 1.01–1.28) for TT, SHBG, and FT, respectively) (26).