IFNG and Huntington disease: Furthermore, HD has been linked to an increase in inflammatory markers such as interleukin-6 (IL-6), interleukin-10 (IL-10), C-reactive protein (CRP), C3, interferon-γ (IFN-γ), interleukin-1 (IL-1), interleukin-2 (IL-2), interleukin-8 (IL-8), and tumor necrosis factor-α (TNF-α) [27].