IL1A and early-onset autosomal dominant Alzheimer disease: While inflammation normallyacts as a protective mechanism, it can cause damage to thebody when it becomes uncontrollable (Dinarello, 2018).IL-1 has been implicated in neuronal cell damage (Allanet al., 2005), and excessive phagocytosis may contribute topathologies in Alzheimer’s disease, schizophrenia, and aging(Vilalta, Brown, 2018).