SYNE1 and Emery-Dreifuss muscular dystrophy: Nine genes have been proved to be involved in the pathogenesis of EDMD: EMD (EDMD1 subtype), LMNA (EDMD2 and EDMD3 subtypes), SYNE1 (EDMD4 subtype), SYNE2 (EDMD5 subtype), FHL1 (EDMD6 subtype), TMEM43 (EDMD7 subtype), SUN1, SUN2, and TTN.211