Nine genes have been proved to be involved in the pathogenesis of EDMD: EMD (EDMD1 subtype), LMNA (EDMD2 and EDMD3 subtypes), SYNE1 (EDMD4 subtype), SYNE2 (EDMD5 subtype), FHL1 (EDMD6 subtype), TMEM43 (EDMD7 subtype), SUN1, SUN2, and TTN.211. This evidence concerns the gene SYNE2 and Emery-Dreifuss muscular dystrophy.