Additionally, Miyazaki et al. (28) showed a case of ARPC and eosinophilic granulomatosis with polyangiitis (EGPA) developing concurrently in a diabetic patient, suggesting that increased secretion of MMP-2 and MMP-9 in EGPA might be associated with collagen degeneration in the skin. This evidence concerns the gene MMP2 and eosinophilic granulomatosis with polyangiitis.