Recent research has also revealed that T. linteus possesses potent anti-breast cancer proliferative activity by downregulating marker of proliferation Kiel 67 (MKI67), Human epidermal growth factor receptor 2 (HER2), epidermal growth factor receptor (EGFR), murine double minute 2 (MDM2), TNFα, and phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PI3KCA) expression [245]. The gene discussed is ERBB2; the disease is breast carcinoma.