Inotodiol (48) and trametenolic acid (49) are common triterpenoids found in I. obliquus, and were found to exert anti-proliferative activities on AGS, MCF-7, and PC3 cancer cells [95], and alleviate liver diseases through modification of the farnesoid X receptor (FXR)/small heterodimer partner (SHP)/ sterol-regulatory element binding protein-1C (SREBP-1C) axis [96]. Here, NR1H4 is linked to cancer.