Extracts from T. linteus growth on germinated brown rice could inhibit NO and PGE2 production as well as reduce iNOS, NF-κB, COX-2, and TNF-α expressions to ameliorate pathological changes of colitis [241], while T. linteus grown on Panax ginseng media could suppress phosphorylation of spleen associated tyrosine kinase, GRB2 associated binding protein 2 (GAB2), and extracellular signal-regulated kinases required for degranulation and release of inflammatory cytokines [242]. This evidence concerns the gene GAB2 and colitis.