In 100 serum samples, expression of TLR1, TLR7, and TLR8 was found to be upregulated in CRC group compared to control groups (~ 12, 11 and 15 folds higher, respectively) (p < 0.01).(Tables S4 & S5, Fig. 3). The gene discussed is TLR7; the disease is colorectal carcinoma.