Regarding serum parameters, a 1-SD increase in alanine transaminase (ALT) was associated with a 1.07-fold increased risk of HCC (OR = 1.07, 95% CI: 1.04–1.10); for AST levels, the OR of HCC increased by1.22 fold (95% CI: 1.12–1.33). This evidence concerns the gene GPT and hepatocellular carcinoma.