This included shared overexpression of many genes that had emerged during the Banner SFG network analysis, including CD83, AC131944.1, SPP1, APOE and ATP1B3. Within the Fujita-ROSMAP (Mathys-ROSMAP) data we observed CD83(+) microglia in 25% (38%) of AD subjects and 4% (24%) of Control subjects. The gene discussed is SPP1; the disease is Alzheimer disease.