Within the Banner SFG snRNA-seq, we did not observe any difference in age of death, sex, ethnicity, post-mortem interval (PMI), neuritic plaque density, neurofibrillary tangle burden, clinical dementia rating or ApoE4 carriage rates between AD subjects with and without CD83(+) microglia (Supplementary Dataset 9). Here, APOE is linked to Alzheimer disease.