Expression of effector molecules was detected in CXCR6+ CD8 T cells after resolved infection, such as Gzmb, Cxcr3, Ccr2 and Ccr5, in contrast to enriched expression of co-inhibitory receptors by CXCR6+ CD8 T cells during persistent hepatic infection, such as Pdcd1 and Lag3 (Fig. 1k). This evidence concerns the gene CXCR6 and infection.