Enhanced tumoral CD44 expression resulted in significantly impaired DSS in the subgroup of patients with nodal-positive GC (DSS: Kaplan Meier/log rank; p = 0.031; Fig. 4) as well as in the overall GC group (DSS: Kaplan Meier/log rank; p = 0.005; Fig. 5), but no impact was found on RFS. Here, CD44 is linked to gastric cancer.