MB had less inflammation than other tumor types (median TIS = 6.58; p = 0.0002 vs. normal brain; Fig. 1c), although SHH-subgroup MB had higher inflammation than other MB subtypes (Fig S3b; median TIS = 7.72; p = 0.01 vs WNT, p = 0.007 vs Group 3, p = 0.004 vs. Group 4), which is consistent with several prior reports25,31. The gene discussed is SHH; the disease is neoplasm.