A K-M prognostic analysis suggested that high levels of tumor-infiltrating Tregs (P = .032), low levels of tumor-infiltrating N1 neutrophils (P < .001), high levels of tumor-infiltrating M2 macrophages (P = .016) and high PD-L1 expression (P = .002) were associated with poor OS, while a high level of infiltrating Tregs was associated with shortened RFS time (P = .011; Supplementary Figures S1 and S3). This evidence concerns the gene CD274 and neoplasm.