To further investigate the impact of Tks4 protein on human lung cancers and to assess whether Tks4 expression levels change during NSCLC development, we analyzed the levels of Tks4 mRNA in samples from patients with lung cancer using the GEPIA2 (Gene Expression Profiling Interactive Analysis) database, which is based on data from TCGA and GTEx (Genotype-Tissue Expression) (Tang et al., 2019). This evidence concerns the gene SH3PXD2B and non-small cell lung carcinoma.