SH3PXD2B and melanoma: Furthermore, Kui et al. explored the prognostic value of Tks4 in hepatocellular carcinoma via a combined multiomics and experimental study (Kui et al., 2021).The potential involvement of Tks4 in metastasis was also reported in a study on lung metastasis-forming melanoma cells in mice (Iizuka et al., 2016).