SH3PXD2B and non-small cell lung carcinoma: The results provided further details on changes in Tks4 expression level during NSCLC progression, as we generally observed that the Tks4 mRNA level is lower in lung cancer tissues compared with healthy tissues (Figure 5, A and C), suggesting its potential as a biomarker for distinguishing between healthy and cancerous lung tissues in patients (Figure 5E).