COL2A1 and nasopharyngeal carcinoma: In vitro culture showed a decrease in the expression of COL2A1 and Aggrecan (ACAN) during monolayered culture of NPC, while the expression of conventional NP-labeled SOX9 and COL2A1, along with NP-specific labeled KRT8, KRT18, and FOXF1, significantly increased in SAPH.