LncRNA MEG3 (Long noncoding maternally Expressed Gene 3) is widely considered a tumor suppressor because it is mostly downregulated in different cancer cell lines and primary human cancers like non-small cell lung cancer (Li et al. 2023), colorectal cancer (Elsherbeny et al. 2023), and osteosarcoma (Huang et al. 2023a, b). This evidence concerns the gene MEG3 and cancer.