On the contrary, Kutlu et al., 2021 reported a conflicting result with the present study on sTREM-1 levels (Pabla and Schwartz 2020) This discrepancy underscores the complexity of the inflammatory response and highlights the need for further investigation to unravel the nuanced effects of IFX and ADA on sTREM-1 in the context of IBD. Here, ADA is linked to inflammatory bowel disease.